Media: Russian scientists learned to grow the retina

СМИ: российские ученые научились выращивать сетчатку глаза

Scientists of the Federal research and clinical center for physical-chemical medicine (fnkts PCN), a unit of the Federal medical-biological Agency (FMBA), learned how to grow a retina from reprogrammed cells; the development will help to cure blindness, said on Thursday the newspaper “Izvestia”.

As the newspaper notes, the first transplantation in clinical trials are going to produce in 2017. With the help of new cell technologies, the researchers plan to subsequently learn how to treat Parkinson’s disease.

“The reprogramming of cells is a relatively new phenomenon in science. The discovery belongs to Professor of Kyoto University Signa Yamanaka. Yamanaka discovered a unique ability of human cells of a particular tissue, such as fibroblasts or skin epithelium, be reprogrammed into an embryonic state. From such undifferentiated (pluripotent) stem cells can be grown in almost any fabric. For example, from skin fibroblasts can be grown the retina. This operation allows to treat, such as patients losing vision due to macular degeneration — a disease which is one of the most frequent causes of blindness in people over 55 years”, — the newspaper quoted Director General of the Federal research and clinical centre FKHM Vadim Govorun.

In the Laboratory of cell biology the newspaper reported that the skin for reprogramming to use the most convenient, because tissue sampling is almost not traumatic for the patient, while the cells reproduce well.

Head of the Laboratory of biomedical technologies, Federal research and clinical centre FKHM Sergei Kiselyov told the newspaper that clinical trial transplant retinal are today in the US and Europe. They were conducted also in Japan, but was temporarily suspended due to changes in legislation, but in 2017 they plan to continue. As for Russia, here the scientists “are waiting for the entry into force of the law “On biomedical cell products” (January 1, 2017) and making it normative acts”, the newspaper writes.

First patients for transplantation of the retina will be people with a hereditary macular dystrophy, say “news”. If age-related form of blindness amenable to some types of treatment, patients with genetic maculodystrophy starting to go blind in 20-30 years, and it has no cure.

Gabby also told that in fnkts PRODUCTS grown and tested on animals the neurons of the brain.

“Their transplantation along with editing of the genome will help in the treatment of patients with Parkinson’s disease. In a world of such clinical trials are already underway. In Russia, they are possible if there is interest from the relevant agencies neurosurgical and neurological institutions — and also only after the adoption of the law” — note the “news”.

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