Scientists: regular use of aspirin to extend the life of older people

Ученые: регулярный прием аспирина продлит жизнь пожилым людям

Continuous administration of low-dose aspirin in the elderly years can significantly reduce the risk of cancer and the occurrence of heart attacks and strokes, which significantly extends the life of older people and will save on medical costs, according to a paper published in the journal PLoS One.

“Of course, we have known about the positive properties of aspirin, but for some reason, few people takes it as a preventive measure. Our study showed that the substance has a positive effect on the body in several ways, and a small amount of this cheap medication will enable us in future to significantly reduce the cost of medicine,” said David Agus (David Agus) from the University of southern California in Beverly hills (USA).

Agus and his colleagues concluded that regular intake of aspirin significantly lowered the costs of the US government to medical care of the population and extend the life of many elderly people, having considered the consequences of taking this medicine a large group of people using a computer model “nursing home”.

In recent years, among scientists has been renewed interest in aspirin and other drugs on the basis of salicylic acid, which experiments have shown to possess strong anti-cancer properties, and improves the chances of survival after chemotherapy by 15-20%. In addition, aspirin dilates blood vessels and significantly reduces the likelihood of death from heart attacks and other problems with the cardiovascular system.

On the other hand, many regulators, including the us FDA recommends against taking aspirin or on the contrary, prevents its acceptance due to the fact that aspirin can cause bleeding and strokes and increase ulcer due to the fact that it can dissolve clots in the blood vessels of the brain and intestines.

A team of Agus tried to account for these effects, following the intake of aspirin affect mortality and life expectancy of a large group of elderly people in a special virtual reality system. To create it, the researchers used real data of observations of how aspirin affects different organs of older people and of the whole organism.

As shown by their calculations, the benefits from regular intake of low-dose aspirin significantly outweigh its side effects – on average, its admission would prolong the lives of Americans for nearly four months, will save about $ 700 billion by 2036 and will save the lives of nearly a million older people. All of this points to the fact that current FDA rules are incorrect, and that aspirin should be actively used for prevention of heart attacks and cancer among the elderly.

“The irony of our discovery is that the problem of aspirin has always been not that it is potentially dangerous, and that it is too cheap. Only 40% of Americans are taking aspirin when you need it, and pharmacists have little incentive to increase this number, despite the benefits of aspirin. We need to figure out how to interest drug companies in this, otherwise it will not move anywhere,” concludes Dana Goldman (Dana Goldman), a colleague of Agusa.