The scientists said, which diet causes the development of «slow» cancer

© Depositphotos / zentiliaМолекулы DNA. Archival photoThe scientists said, which diet causes the development of «slow» cancer© Depositphotos / zentilia

Scientists from medical centre Beth Israel found a link between the genetic mechanism that triggers the process of metastasis of a malignant tumor of the prostate, and saturated fat diet typical of Western countries. Press release of the study available on the portal Medical Xpress.

Experts have established that the slow («slow») prostate cancer in terms of lack of the genes PTEN and PTL generates a large amount of fat. «It felt like we had found a switch for the production of these substances, — said the head of a group of scientists pier Paolo Pandolfi. — If there is such a switch should have a cure by which we will be able to block it and prevent the emergence of metastases or even cure metastatic cancer.»

It is noted that gene-tumor suppressor gene PTEN plays an important role in the development of the disease the partial loss starts a carcinogenic process, and the complete loss of that portion of the DNA associated with the formation of metastases. The destruction of the structures of another gene PTL – also strongly activates tumor growth.

In the experiment, the researchers moved on «fastfude» diet group of rodents. After some time in the organisms of mice with damaged genes PTEN and PTL began an active process of metastasis. It is noted that after the start of treatment experimental drugs for obesity in the development of the disease have been suspended.

«Although it is widely known that the Western diet may contribute to the development of prostate cancer, direct evidence of this connection was not enough,» said one of the authors, Dr. Ming Chen. However, he noted that only now managed to establish a dependency between fastfudom and the occurrence of malignant neoplasms.