Scientists from Canada have created the «eternal» fillings for teeth

© Depositphotos / SimpleFotoДевушка eating an AppleScientists from Canada have created the «eternal» fillings for teeth© Depositphotos / SimpleFoto

. Canadian chemists have created a new type of seal that protects the teeth from further attacks of microbes by nanoparticles of antibiotics embedded in their surface, according to an article published in the journal Nature Communications.

«Nanoparticles filled with antibiotics that make the seal in the first line of defense against germs that cause tooth decay. Usually these fillers worked only a couple of weeks. We managed to find a combination of drugs and silicon nanoparticles, which contain a sufficient number of substances, which is enough to protect teeth for many years,» says Ben Hutton (Ben Hatton) from the University of Toronto (Canada).

As the scientists explain, even with all the technological procedures at the border fillings eventually formed microsensor in which thrive microorganisms. In addition, tissues of the tooth and the material of the seal in different ways repel water, which also creates problems when the installation of the seal and its further «life» part of the tooth.

In recent years, scientists, as told by Hutton, came to the conclusion that this problem can be solved by making the seal «poisonous» for microbes, filling it with antibiotics and other substances, in contact with which the bacteria are destroyed. The first experiments confirmed that this idea works well, but put the scientists in front of a difficult task – it turned out that antibiotics are rapidly leached out of the fillings and so it is protected very long.

As the scientists explain, this is due to one simple thing – how manufactured nanoparticles containing antibiotics. As a rule, they consist of a hollow or porous spheres of silicon and other chemically inert substances, which are first made and then filled with drugs. In most cases, antibiotics are present only on their surface, and their total mass inside the nanoparticles always remains extremely small.

Canadian chemists have tried to eliminate this disadvantage of the nanoparticles, with a technology of their manufacture, in which the molecules of the antibiotics get into the pores of the nanoparticles during their Assembly. This allowed them to increase the proportion of antibiotic inside them about 50 times and sharply reduce the rate of escape of molecules from the surface of such granules.

As shown by the first experiments of scientists like nanoparticles continued to kill the strep that causes dental caries, and many other microbes even two years after their production, suggests that they can protect the teeth throughout the life of the bearer of such fillings.

Interestingly, similar seals were created by scientists from the Russian nust «MISIS» and checked in one of the Moscow dental clinics. Unlike their foreign colleagues, the Russian chemists used nanoparticles of metals, not antibiotics, making them potentially more durable.

Source